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R&D

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Research areas/Development achievements

TECHNOLOGY PLATFORM
Supercritical & Biomaterial Technology Platform

DOF Inc. Product-related Papers

SC Connect
Title
Supercritical carbon dioxide decellularization of porcine nerve matrix for regenerative medicine
Authors
Linh Thi Thuy Le, Chien Ngoc Pham, Xuan-Tung Trinh, Giang Ngan Nguyen, Long Van Nguyen, Sun-Young Nam, and Heo Chan-Yeong
Publication Date
2024.01.11
Journal Name
Tissue Engineering, Part A : Research Advances
ISSN
1937-3341
SCDerm
Title
Effective decellularization of human skin tissue for regenerative medicine by supercritical carbon dioxide technique
Authors
Nguyen Ngan Giang, Xuan‐Tung Trinh, Jeonghun Han, Pham Ngoc Chien, Jua Lee, Seong‐Rae Noh, Yongwoo Shin, Sun‐Young Nam, Chan‐Yeong Heo
Publication Date
2022.11.08
Journal Name
Journal of tissue engineering and regenerative medicine
ISSN
1932-6254
Fundamental Study
Title
Supercritical Fluid-Based Decellularization Technologies for Regenerative Medicine Applications
Authors
Beom-Seok Kim, Jeong-Uk Kim, Kyoung-Ha So, and Nathaniel S. Hwang
Publication Date
2021.08.21
Journal Name
Macromolecular bioscience
ISSN
1616-5187
Conductive Films
Title
Optoelectrical Properties of Transparent Conductive Films Fabricated with Ag Nanoparticle-Suspended Emulsion under Various Formulations and Coating Conditions
Authors
Seong Hwan Kim, Geunyeop Park, Kyu-Byung Kim, Yong-Woo Shin and Hyun Wook Jung
Publication Date
2023.04.27
Journal Name
Nanomaterials
ISSN
2079-4991

Status of domestic and international patents

Domestic patents Registered patent No.
10-2456445
10-2491964
10-2333417
10-2122032
10-2136397
10-2071415
10-2009424
10-1956672
10-1954905
10-1908071
Application No. for patent
10-2022-0043858
10-2022-0190226
10-2022-0177819
10-2023-0150782
10-2023-0154639
10-2023-0192623
10-2023-0194099
10-2024-0006887
10-2024-0041517
10-2024-0041519
International patents Registered patent No.
US 11655270
CN 114286694
Application No. for patent
KR PCT-KR2019-016189
KR PCT-KR2022-021695
KR PCT-KR2023-002604
US 17/594602
CN 2019-80086956
Trademark application Registered patent No.
40-17554120000
40-2087248
40-2069243
40-2090232
Application No. for patent
40-2022-0044800
40-2022-0044801
40-2022-0204390
40-2023-0151295
40-2023-0151300
40-2023-0156444
40-2024-0045287
40-2024-0060347
40-2024-0087638

Current Development Plans
for Human Tissue or Medical Device

Human Tissues
  • SC matrix
  • SC bone powder
  • SC vessel
Medical Devices
  • Wound Care Products : Negative Pressure Wound Dressing, Foam Dressing, Hydrocolloid
  • Surgical Supplies: Anti-adhesive Agents, Hemostatic Agents
  • Aesthetic and Plastic Surgery: Skin Boosters, Dermal Fillers, Heterologous Cartilage (Nose Reshaping)
  • Interventional Medical Devices: TAVI (Transcatheter Aortic Valve Implantation)
SCFILL POWDER
  • Used in Urology for Penile Augmentation and in Gynecology for Vaginal Plastic Surgery
  • In the surgical setting, skin powders are mixed with HA hydrogel or saline to create the desired form for application.